Recombinant Human NANS, His-tagged

PRODUCTS

Home / Products / Recombinant Proteins / Recombinant Human NANS, His-tagged

Recombinant Human NANS, His-tagged

NANS Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : NANS-28783TH
Product Overview : Recombinant full length Human NANS with N terminal His tag; 379 amino acids with tag; MWt 42.4kDa.
Description : This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
Protein length : 359 amino acids
Conjugation : HIS
Molecular Weight : 42.400kDa inclusive of tags
Source : E. coli
Tissue specificity : Ubiquitous.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHHSSGLV PRGSHMPLELELCPG RWVGGQHPCFIIAEI GQNHQGDLDVAKRMI RMAKECGADCAKFQK SELEFKFNRKALERP YTSKHSWGKTYGEHK RHLEFSHDQYRELQR YAEEVGIFFTASGMD EMAVEFLHELNVPFF KVGSGDTNNFPYLEK TAKKGRPMVISSGMQ SMDTMKQVYQIVKPL NPNFCFLQCTSAYPL QPEDVNLRVISEYQK LFPDIPIGYSGHETG IAISVAAVALGAKVL ERHITLDKTWKGSDH SASLEPGELAELVRS VRLVERALGSPTKQL LPCEMACNEKLGKSV VAKVKIPEGTILTMD MLTVKVGEPKGYPPE DIFNLVGKKVLVTVE EDDTIMEELVDNHGK KIKS
Sequence Similarities : Contains 1 AFP-like domain.
Gene Name : NANS N-acetylneuraminic acid synthase [ Homo sapiens ]
Official Symbol : NANS
Synonyms : NANS; N-acetylneuraminic acid synthase; sialic acid synthase; SAS;
Gene ID : 54187
mRNA Refseq : NM_018946
Protein Refseq : NP_061819
MIM : 605202
Uniprot ID : Q9NR45
Chromosome Location : 9p24.1-p23
Pathway : Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; CMP-N-acetylneuraminate biosynthesis I (eukaryotes), conserved biosystem; Metabolic pathways, organism-specific biosystem; superpathway of sialic acid and CMP-sialic acid biosynthesis, conserved biosystem;
Function : N-acetylneuraminate synthase activity; N-acylneuraminate cytidylyltransferase activity; N-acylneuraminate-9-phosphate synthase activity; transferase activity;

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved.