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Recombinant Human NCOA1, FLAG-tagged

Cat.No. : NCOA1-29883TH
Product Overview : Recombinant fragment, corresponding to amino acids 627-786 of Human KAT13A / SRC1 with Flag tag, Predicted MWt 18 kDa.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.
Conjugation : FLAG
Source : E. coli
Tissue specificity : Widely expressed.
Form : Liquid
Purity : Immunogen affinity purified
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the SRC/p160 nuclear receptor coactivator family.Contains 1 basic helix-loop-helix (bHLH) domain.Contains 1 PAS (PER-ARNT-SIM) domain.
Gene Name : NCOA1 nuclear receptor coactivator 1 [ Homo sapiens ]
Official Symbol : NCOA1
Synonyms : NCOA1; nuclear receptor coactivator 1; bHLHe74; F SRC 1; KAT13A; NCoA 1; RIP160; SRC1;
Gene ID : 8648
mRNA Refseq : NM_003743
Protein Refseq : NP_003734
MIM : 602691
Uniprot ID : Q15788
Chromosome Location : 2p23
Pathway : Adipogenesis, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Energy Metabolism, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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