Recombinant Human Selectin L, Fc-His
Cat.No. : | SELL-1660H |
Product Overview : | Recombinant Human SELL was expressed inNSOcells. The extracellular domain of human L-Selectin (amino acid residues 1-332) was fused to the carboxy-terminal 6X his tagged Fc region of human IgG1 via a polypeptide linker. |
- Specification
- Gene Information
- Related Products
Cat. No. : | SELL-1660H |
Description : | L-selectin, also known as CD62L, is a cell adhesion molecule consisting of a large, highly glycosylated, extracellular domain found on leukocytes. It belongs to the selectin family of proteins, which recognise sialylated carbohydrate groups. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via the high endothelial venules. L-selectin is an effective marker for separating lymphoid progenitors from myeloid progenitors and hematopoietic stem cells in bone marrow. |
Molecular Weight : | The predicted molecular weight of Recombinant Human L-Selectin is Mr 60.4 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 90-100 kDa under reducing conditions. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Formulation : | This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives. |
Purity : | >90% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Biological Activity : | The biological activity of Human L-Selectin was determined by the ability of the immobilized protein to support the adhesion of LS180 cells, a human colon adenocarcinoma cell line. When 1 x 104 cells/well are added to human L-Selectin coated plates (10 μg/ml with 100 μl/well), approximately 90 - 100% will adhere for 1 hour incubation at RT. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | SELL selectin L [ Homo sapiens ] |
Synonyms : | SELL; selectin L; CD62L; LAM1; LECAM1; LEU8; LNHR; LSEL; LYAM1; PLNHR; TQ1; CD62 antigen-like family member L; L-selectin; gp90-MEL; leukocyte adhesion molecule-1; leukocyte surface antigen Leu-8; leukocyte-endothelial cell adhesion molecule 1; lymph node homing receptor; lymphocyte adhesion molecule 1; pln homing receptor; CD62L antigen; Leukocyte adhesion molecule 1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; Lymph node homing receptor |
Gene ID : | 6402 |
mRNA Refseq : | NM_000655 |
Protein Refseq : | NP_000646 |
MIM : | 153240 |
UniProt ID : | P14151 |
Chromosome Location : | 1q23-q25 |
Pathway : | Cell adhesion molecules (CAMs); Hemostasis; Signaling in Immune system |
Function : | glycosphingolipid binding; heparin binding; protein binding; sugar binding |
Products Types
◆ Recombinant Protein | ||
SELL-936R | Recombinant Rat SELL Protein (Met1-Asn332), His-tagged | +Inquiry |
SELL-3949R | Recombinant Rhesus Macaque SELL Protein, His (Fc)-Avi-tagged | +Inquiry |
SELL-233H | Recombinant Human SELL Protein, His (Fc)-Avi-tagged | +Inquiry |
SELL-227H | Recombinant Human SELL Protein, His-tagged | +Inquiry |
Sell-5756M | Recombinant Mouse Sell Protein, His-tagged | +Inquiry |
◆ Lysates | ||
SELL-2614MCL | Recombinant Mouse SELL cell lysate | +Inquiry |
SELL-1131CCL | Recombinant Cynomolgus SELL cell lysate | +Inquiry |
SELL-1963HCL | Recombinant Human SELL cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket