Recombinant Human NR1D2

• Cat.No.: NR1D2-30452TH
• Product Overview: Recombinant full length human NR1D2 expressed in baculovirus system; amino acids 1-408, 46kDa.

Specification

• Description: This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
• Biological activity: NR1D2-30452TH contains no detectable proteases, DNase and RNase activity.
• Form: Liquid
• Purity: Immunogen affinity purified
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the nuclear hormone receptor family. NR1 subfamily.Contains 1 nuclear receptor DNA-binding domain.

Gene Information

• Gene Name: NR1D2 nuclear receptor subfamily 1, group D, member 2 [ Homo sapiens ]
• Official Symbol: NR1D2
• Synonyms: NR1D2; nuclear receptor subfamily 1, group D, member 2; nuclear receptor subfamily 1 group D member 2; BD73; EAR 1r; Hs.37288; HZF2; RVR
• Gene ID: 9975
• mRNA Refseq: NM_001145425
• Protein Refseq: NP_001138897
• MIM: 602304
• Uniprot ID: Q14995
• Chromosome Location: 3p24.1
• Pathway: Diurnally regulated genes with circadian orthologs, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem
• Function: ligand-dependent nuclear receptor activity; metal ion binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity