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Recombinant Human Tumor-associated Calcium Signal Transducer 2

Cat.No. : TACSTD2-1694H
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  • Gene Information
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Cat. No. : TACSTD2-1694H
Description : Trop-2 is a cell surface glycoprotein that is highly expressed in a wide variety of epithelial cancers. There is little or no expression of Trop-2 in adult somatic tissue. Trop-2 is a novel calcium signal transducer involved in the regulation of cell- cell adhesion. It is an oncogene that has potential as a therapeutic target. It is a possible candidate gene for diagnosis and molecular target therapy of colorectal cancer.
Molecular Weight : The predicted molecular weight of Recombinant Human TROP-2 is Mr 49.2 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 70-80 kDa.
Source : Mammalian cells
State Of Matter : Lyophilized.
Purity : >95% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : TACSTD2 tumor-associated calcium signal transducer 2 [ Homo sapiens ]
Synonyms : TACSTD2; tumor-associated calcium signal transducer 2; M1S1; EGP-1; GA733; TROP2; GA733-1; epithelial glycoprotein-1; membrane component, chromosome 1, surface marker 1 (40kD glycoprotein, identified by monoclonal antibody GA733); Cell surface glycoprotein Trop-2; Pancreatic carcinoma marker protein GA733-1; OTTHUMP00000011755
Gene ID : 4070
mRNA Refseq : NM_002353
Protein Refseq : NP_002344
MIM : 137290
UniProt ID : P09758
Chromosome Location : 1p32
Function : receptor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What diagnostic techniques are used to assess TACSTD2 levels in cancer patients? 11/29/2022

Immunohistochemistry and PCR-based assays are common techniques to measure TACSTD2 expression in cancer tissues.

How does TACSTD2 contribute to cancer metastasis? 05/17/2020

TACSTD2 promotes cancer cell migration and invasion, leading to metastasis by interacting with various signaling pathways.

Are there clinical trials involving TACSTD2-targeted therapies for cancer treatment? 11/06/2018

Yes, there are ongoing clinical trials testing TACSTD2-targeted therapies, including antibody-drug conjugates and immunotherapies.

What are the potential side effects of TACSTD2-targeted therapies? 09/29/2017

Common side effects can include fatigue, nausea, diarrhea, and skin rashes, similar to other cancer treatments.

Are there any targeted therapies that focus on TACSTD2? 04/30/2017

Yes, monoclonal antibodies and antibody-drug conjugates targeting TACSTD2 are being investigated for cancer treatment.

Customer Reviews (3)

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Reviews
06/05/2020

    In addition to its advantages in trials, the manufacturer of the TACSTD2 protein offers exceptional support to researchers.

    06/11/2018

      Their team of technical experts possess deep knowledge and expertise regarding the protein, ensuring that researchers receive accurate and timely assistance.

      01/24/2018

        the TACSTD2 protein has been extensively studied and validated in various experimental applications.

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