||Trop-2 is a cell surface glycoprotein that is highly expressed in a wide variety of epithelial cancers. There is little or no expression of Trop-2 in adult somatic tissue. Trop-2 is a novel calcium signal transducer involved in the regulation of cell- cell adhesion. It is an oncogene that has potential as a therapeutic target. It is a possible candidate gene for diagnosis and molecular target therapy of colorectal cancer.
||The predicted molecular weight of Recombinant Human TROP-2 is Mr 49.2 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 70-80 kDa.
|State Of Matter:
||>95% by SDS Page and analyzed by silver stain.
||<1.0 EU/µg as determined by the LAL method.
|Storage And Stability:
||This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.