Recombinant Human PAWR
Cat.No. : | PAWR-28664TH |
Product Overview : | Recombinant fragment of Human PAR4 with N-terminal proprietary tag.Mol Wt 37.73 kDa inclusive of tag. |
- Specification
- Gene Information
- Related Products
Description : | The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells. |
Protein length : | 110 amino acids |
Molecular Weight : | 37.730kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Widely expressed. Expression is elevated in various neurodegenerative diseases such as amyotrophic lateral sclerosis, Alzheimer, Parkinson and Huntington diseases and stroke. Down-regulated in several cancers. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | SVSEEDVSSRYSRTDRSGFPRYNRDANVSGTLVSSSTLEK KIEDLEKEVVRERQENLRLVRLMQDKEEMIGKLKEEIDLL NRDLDDIEDENEQLKQENKTLLKVVGQLTR |
Gene Name : | PAWR PRKC, apoptosis, WT1, regulator [ Homo sapiens ] |
Official Symbol : | PAWR |
Synonyms : | PAWR; PRKC, apoptosis, WT1, regulator; PRKC apoptosis WT1 regulator protein; par 4; PAR4; |
Gene ID : | 5074 |
mRNA Refseq : | NM_002583 |
Protein Refseq : | NP_002574 |
MIM : | 601936 |
Uniprot ID : | Q96IZ0 |
Chromosome Location : | 12q21.2 |
Pathway : | Ceramide signaling pathway, organism-specific biosystem; Coregulation of Androgen receptor activity, organism-specific biosystem; IL-4 signaling Pathway, organism-specific biosystem; |
Function : | actin binding; enzyme binding; leucine zipper domain binding; protein binding; transcription corepressor activity; |
Products Types
◆ Recombinant Protein | ||
Pawr-528M | Recombinant Mouse Pawr Protein, MYC/DDK-tagged | +Inquiry |
PAWR-6514M | Recombinant Mouse PAWR Protein, His (Fc)-Avi-tagged | +Inquiry |
PAWR-3944R | Recombinant Rat PAWR Protein, His (Fc)-Avi-tagged | +Inquiry |
PAWR-359H | Recombinant Human PAWR protein, His-tagged | +Inquiry |
PAWR-12389M | Recombinant Mouse PAWR Protein | +Inquiry |
◆ Lysates | ||
PAWR-3420HCL | Recombinant Human PAWR 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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