"PDXK" Related Products

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Recombinant Human PDXK, His-tagged

Cat.No.: PDXK-29673TH
Product Overview: Recombinant full length Human PDXK.1 with N terminal His tag; 336 amino acids with tag, Predicted MWt 37.6 kDa.
Description: The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Protein length: 312 amino acids
Conjugation: HIS
Molecular Weight: 37.600kDa inclusive of tags
Source: E. coli
Tissue specificity: Ubiquitous. Isoform 3 is detected in adult testis and spermatozoa.
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMGSHMEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDIEDPEIVVQATVL
Sequence Similarities: Belongs to the pyridoxine kinase family.
Gene Name: PDXK pyridoxal (pyridoxine, vitamin B6) kinase [ Homo sapiens ]
Official Symbol: PDXK
Synonyms: PDXK; pyridoxal (pyridoxine, vitamin B6) kinase; C21orf97, C21orf124, chromosome 21 open reading frame 97 , chromosome 21 open reading frame 124; pyridoxal kinase; FLJ21324; FLJ31940; MGC15873; PKH; PNK; PRED79;
Gene ID: 8566
mRNA Refseq: NM_003681
Protein Refseq: NP_003672
MIM: 179020
Uniprot ID: O00764
Chromosome Location: 21q22.3
Pathway: Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of vitamins and cofactors, organism-specific biosystem; Metabolism of water-soluble vitamins and cofactors, organism-specific biosystem; Vitamin B6 metabolism, organism-specific biosystem;
Function: ATP binding; lithium ion binding; magnesium ion binding; nucleotide binding; potassium ion binding;

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