Recombinant Human Zinc Finger, GATA-Like Protein 1
Cat.No. : | ZGLP1-167H |
Product Overview : | Recombinant Human zinc finger, GATA-like protein 1 was expressed inhumanCells andThe sequence of the first five N-terminal amino acids was determined and was found to be His-Ala-Glu-Gly-Thr. |
- Specification
- Gene Information
- Related Products
Cat. No. : | ZGLP1-167H |
Description : | Glucagon-like peptide-1 (GLP-1) formerly called insulinotropin, is a metabolic hormone derived from the transcription product of the proglucagon gene. GLP-1 is a physiologic mediator of satiety and regulates energy absorption and disposal. GLP-1 stimulate secretion of insulin in the presence of elevated blood glucose concentrations, but not during periods of low blood glucose concentrations (hypoglycemia). GLP-1 is a potent stimulator of insulin release in pancreas and has the ability to render pancreatic beta-cells glucose-competent. It has been used in the therapy of type 2 diabetes. |
Source : | human cells. |
Molecular Weight : | The predicted molecular weight of Recombinant Human GLP-1 is 33 kD kDa. |
State Of Matter : | Lyophilized. |
Formulation : | Lyopohilized with no additives. |
Purity : | >98% by SDS Page and HPLC. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Biological Activity : | The biological activity of Human GLP-1 was determined by: 1. Regulates Glucose levels rapidly 2. Reduces Insulin resistence 3. Reduces Glucagon 4. Reduces HbA1c 5. Stimulates beta cell grwoth which stimulates insulin production. |
Storage : | The lyophilized protein should be stored desiccated at -20℃. The reconstituted protein can be stored for at least one week at 4℃. For long-term storage of the reconstituted protein, aliquot into working volumes and store at -20℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
Gene Name : | ZGLP1 zinc finger, GATA-like protein 1 [ Homo sapiens ] |
Synonyms : | ZGLP1; zinc finger, GATA-like protein 1; GLP1; GLP-1; FLJ39511; FLJ39703; GATA like protein 1 |
Gene ID : | 100125288 |
mRNA Refseq : | NM_001103167 |
Protein Refseq : | NP_001096637 |
MIM : | 611639 |
UniProt ID : | P0C6A0 |
Chromosome Location : | 19p13.2 |
Function : | metal ion binding; sequence-specific DNA binding; transcription factor activity; transcription repressor activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
ZGLP1-10375M | Recombinant Mouse ZGLP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ZGLP1-4394Z | Recombinant Zebrafish ZGLP1 | +Inquiry |
ZGLP1-941H | Recombinant Human Zinc Finger, GATA-like Protein 1 | +Inquiry |
ZGLP1-19171M | Recombinant Mouse ZGLP1 Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionYes, the expression level of ZGLP1 protein may be affected by environmental factors such as nutritional status, inflammatory response, oxidative stress, etc. These factors may affect the expression of ZGLP1 protein by regulating gene transcription and translation levels.
ZGLP1 protein is mainly distributed in the liver, kidney, heart, skeletal muscle and other tissues of the human body.
Due to the important role of ZGLP1 protein in cell growth and differentiation, it may become an important target for drug discovery. Drugs targeting the ZGLP1 protein may have the potential to modulate cell growth and differentiation.
There is currently no way to directly increase the expression level or activity of ZGLP1 protein. However, its expression levels or activity can be affected by modulating the signal transduction pathways associated with it.
The current research on the expression level of ZGLP1 protein as a biomarker for disease diagnosis or prognosis is insufficient and needs to be further validated.
There are still some challenges and controversies in the current research on ZGLP1 protein, including its specific mechanism of action in different cell types and disease states, its interaction with other molecules, and the optimal treatment.
Customer Reviews (3)
Write a reviewThe results of multiple experiments are highly consistent and the reproducibility is particularly good.
Very good product, great for western-blot.
It can be dissolved in many types of reagents for easy handling.
Ask a Question for All ZGLP1 Products
Required fields are marked with *
My Review for All ZGLP1 Products
Required fields are marked with *
Inquiry Basket