"POLR2I" Related Products


Recombinant Human POLR2I

Cat.No.: POLR2I-30766TH
Product Overview: Recombinant full length human RNA Polymerase II p14.5 with proprietary tag; amino acids 1-125, approximately 41kDa.
Description: This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity.
Source: E. coli
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Gene Name: POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa [ Homo sapiens ]
Official Symbol: POLR2I
Synonyms: POLR2I; polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa; polymerase (RNA) II (DNA directed) polypeptide I (14.5kD); DNA-directed RNA polymerase II subunit RPB9; hRPB14.5; RPB9;
Gene ID: 5438
mRNA Refseq: NM_006233
Protein Refseq: NP_006224
MIM: 180662
Uniprot ID: P36954
Chromosome Location: 19q12
Pathway: Abortive elongation of HIV-1 transcript in the absence of Tat, organism-specific biosystem; DNA Repair, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Eukaryotic Transcription Initiation, organism-specific biosystem; Formation and Maturation of mRNA Transcript, organism-specific biosystem;
Function: DNA binding; DNA-directed RNA polymerase activity; metal ion binding; contributes_to protein kinase activity; zinc ion binding;

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