Recombinant Human PRKCQ
Cat.No. : | PRKCQ-30178TH |
Product Overview : | Recombinant full length Human PKC theta with an N terminal enzyme tag.Expressed by Baculovirus in Sf9 insect cells. |
- Specification
- Gene Information
- Related Products
Description : | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. |
Tissue specificity : | Skeletal muscle, megakaryoblastic cells and platelets. |
Biological activity : | Specific activity: 792 nmol/min/mg |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.Contains 1 AGC-kinase C-terminal domain.Contains 1 C2 domain.Contains 2 phorbol-ester/DAG-type zinc fingers.Contains 1 protein kinase domain. |
Gene Name : | PRKCQ protein kinase C, theta [ Homo sapiens ] |
Official Symbol : | PRKCQ |
Synonyms : | PRKCQ; protein kinase C, theta; protein kinase C theta type; |
Gene ID : | 5588 |
mRNA Refseq : | NM_001242413 |
Protein Refseq : | NP_001229342 |
MIM : | 600448 |
Uniprot ID : | Q04759 |
Chromosome Location : | 10p15 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; |
Function : | ATP binding; metal ion binding; nucleotide binding; protein binding; protein kinase C activity; |
Products Types
◆ Recombinant Protein | ||
PRKCQ-3425R | Recombinant Rhesus Macaque PRKCQ Protein, His (Fc)-Avi-tagged | +Inquiry |
PRKCQ-5522Z | Recombinant Zebrafish PRKCQ | +Inquiry |
PRKCQ-916H | Recombinant Human Protein Kinase C, Theta, His-tagged | +Inquiry |
PRKCQ-5995H | Recombinant Human PRKCQ Protein (Phe380-Phe634), N-GST tagged | +Inquiry |
PRKCQ-3607R | Recombinant Rhesus monkey PRKCQ Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PRKCQ-1416HCL | Recombinant Human PRKCQ cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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