|Product Overview :
||Recombinant full length Protein Kinase D2 protein (Human), was expressed by baculovirus in Sf9 insect cells using a N-terminal tag, MW 130 kDa.
||The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.
|Tissue specificity :
|Storage buffer :
||Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
||Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
|Sequence Similarities :
||Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.Contains 1 PH domain.Contains 2 phorbol-ester/DAG-type zinc fingers.Contains 1 protein kinase domain.