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Recombinant Human PRKD2

Cat.No. : PRKD2-30220TH
Product Overview : Recombinant full length Protein Kinase D2 protein (Human), was expressed by baculovirus in Sf9 insect cells using a N-terminal tag, MW 130 kDa.
Description : The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.
Tissue specificity : Widely expressed.
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.Contains 1 PH domain.Contains 2 phorbol-ester/DAG-type zinc fingers.Contains 1 protein kinase domain.
Gene Name : PRKD2 protein kinase D2 [ Homo sapiens ]
Official Symbol : PRKD2
Synonyms : PRKD2; protein kinase D2; serine/threonine-protein kinase D2; DKFZP586E0820; HSPC187; PKD2;
Gene ID : 25865
mRNA Refseq : NM_001079880
Protein Refseq : NP_001073349
MIM : 607074
Uniprot ID : Q9BZL6
Chromosome Location : 19q13.2
Pathway : T Cell Receptor Signaling Pathway, organism-specific biosystem;
Function : ATP binding; metal ion binding; nucleotide binding; protein kinase C activity; protein kinase activity;

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