Recombinant Human PSIP1, His-tagged

• Cat.No.: PSIP1-31222TH
• Product Overview: Recombinant fragment,corresponding to amino acids 322-530 of human PSIP1 with His tag, 34kDa.

Specification

• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), i
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the HDGF family.Contains 1 PWWP domain.

Gene Information

• Gene Name: PSIP1 PC4 and SFRS1 interacting protein 1 [ Homo sapiens ]
• Official Symbol: PSIP1
• Synonyms: PSIP1; PC4 and SFRS1 interacting protein 1; PC4 and SFRS1 interacting protein 2 , PSIP2; PC4 and SFRS1-interacting protein; LEDGF; p52; p75
• Gene ID: 11168
• mRNA Refseq: NM_001128217
• Protein Refseq: NP_001121689
• MIM: 603620
• Uniprot ID: O75475
• Chromosome Location: 9p22.2
• Pathway: 2-LTR circle formation, organism-specific biosystem; APOBEC3G mediated resistance to HIV-1 infection, organism-specific biosystem; Autointegration results in viral DNA circles, organism-specific biosystem; Early Phase of HIV Life Cycle, organism-specific biosystem; HIV Infection, organism-specific biosystem
• Function: DNA binding; RNA polymerase II transcription coactivator activity; activating transcription factor binding; chromatin binding; protein binding