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Recombinant Human PTGES2, His-tagged

Cat.No. : PTGES2-30326TH
Product Overview : Recombinant full length Human PTGES2 with an N terminal His tag; 206 amino acids with the tag; predicted mwt: 23.5 kDa.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene.
Protein length : 206 amino acids
Conjugation : HIS
Molecular Weight : 23.500kDa inclusive of tags
Source : E. coli
Tissue specificity : Widely expressed. Expressed in the heart, including apex, inter-ventricular septum, both atria and ventricles, but not in the aorta. Also expressed in fetal heart. Detected in various regions of the brain: cerebellum; occipital, frontal and parietal lobes
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 0.2M Sodium chloride, 20mM Tris HCl, 2mM DTT, pH 8.0
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHHSSGLVPRGSHMKAVN EQGKEVTEFGNKYWLMLNEKEAQQV YGGKEARTEEMKWRQWADDWLVHLI SPNVYRTPTEALASFDYIVREGKFG AVEGAVAKYMGAAAMYLISKRLKSR HRLQDNVREDLYEAADKWVAAVGKD RPFMGGQKPNLADLAVYGVLRVMEG LDAFDDLMQHTHIQPWYLRVERAIT EASPAH
Sequence Similarities : Belongs to the GST superfamily.Contains 1 glutaredoxin domain.Contains 1 GST C-terminal domain.
Gene Name : PTGES2 prostaglandin E synthase 2 [ Homo sapiens ]
Official Symbol : PTGES2
Synonyms : PTGES2; prostaglandin E synthase 2; C9orf15, chromosome 9 open reading frame 15; FLJ14038;
Gene ID : 80142
mRNA Refseq : NM_025072
Protein Refseq : NP_079348
MIM : 608152
Uniprot ID : Q9H7Z7
Chromosome Location : 9q34.12
Pathway : Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Eicosanoid Synthesis, organism-specific biosystem; IFN-gamma pathway, organism-specific biosystem; Metabolic pathways, organism-specific biosystem;
Function : DNA binding; electron carrier activity; isomerase activity; prostaglandin-E synthase activity; protein disulfide oxidoreductase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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