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Recombinant Rat Glial Cell Derived Neurotrophic Factor

Cat. No. : Gdnf-359R
Description : Glial cell derived neurotrophic factor, also known as GDNF is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta superfamily. GDNF potently promotes the survival of many types of neurons, most prominently, dopaminergic and motorneurons. GDNF regulates kidney development and spermatogenesis, and it affects alcohol consumption.
Source : Sf 21 Insect Cells.
Amino Acid Sequence : Ser78-Ile211.
Molecular Weight : The predicted molecular weight of Recombinant Rat GDNF is Mr 15 kDa.
State Of Matter : Lyophilized.
Formulation : 0.2 μm filtered and lyophilized from a solution of Acetonitrile and TFA.
Purity : >97% by SDS Page and analyzed by silver stain.
Endotoxin : <0.1 ng per 1 µg as determined by the LAL method.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
GDNF structure. :

Gene Name : Gdnf glial cell derived neurotrophic factor [ Rattus norvegicus ]
Synonyms : Gdnf; glial cell derived neurotrophic factor; Glial cell line derived neutrophic factor
Gene ID : 25453
mRNA Refseq : NM_019139
Protein Refseq : NP_062012
UniProt ID : Q07731
Chromosome Location : q16
Function : glial cell line-derived neurotrophic factor receptor binding; growth factor activity; protein homodimerization activity

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