Recombinant Human RDBP, His-tagged
Cat.No. : | RDBP-29224TH |
Product Overview : | Recombinant full length Human NELFe with an N terminal His tag; 400 amino acids with tag, Predicted MWt 45.4 kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. |
Protein length : | 380 amino acids |
Conjugation : | HIS |
Molecular Weight : | 45.400kDa inclusive of tags |
Source : | E. coli |
Tissue specificity : | Widely expressed. Expressed in heart, brain, lung, placenta, liver, skeletal muscle, kidney and pancreas. |
Form : | Liquid |
Purity : | by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 2mM DTT, pH 8.0 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHHSSGLVPRGSHMLVIP PGLSEEEEALQKKFNKLKKKKKALL ALKKQSSSSTTSQGGVKRSLSEQPV MDTATATEQAKQLVKSGAISAIKAE TKNSGFKRSRTLEGKLKDPEKGPVP TFQPFQRSISADDDLQESSRRPQRK SLYESFVSSSDRLRELGPDGEEAEG PGAGDGPPRSFDWGYEERSGAHSSA SPPRSRSRDRSHERNRDRDRDRERD RDRDRDRDRERDRDRDRDRDRDRER DRDRERDRDRDREGPFRRSDSFPER RAPRKGNTLYVYGEDMTPTLLRGAF SPFGNIIDLSMDPPRNCAFVTYEKM ESADQAVAELNGTQVESVQLKVNIA RKQPMLDAATGKSVWGSLAVQNSPK GCHRDKRTQIVYSDDVYKENLVDGF |
Sequence Similarities : | Belongs to the RRM NELF-E family.Contains 1 RRM (RNA recognition motif) domain. |
Gene Name : | RDBP RD RNA binding protein [ Homo sapiens ] |
Official Symbol : | RDBP |
Synonyms : | RDBP; RD RNA binding protein; negative elongation factor E; D6S45; NELF E; RD; RDP; |
Gene ID : | 7936 |
mRNA Refseq : | NM_002904 |
Protein Refseq : | NP_002895 |
MIM : | 154040 |
Uniprot ID : | P18615 |
Chromosome Location : | 6p21.3 |
Pathway : | Abortive elongation of HIV-1 transcript in the absence of Tat, organism-specific biosystem; Formation and Maturation of mRNA Transcript, organism-specific biosystem; Formation of HIV-1 elongation complex containing HIV-1 Tat, organism-specific biosystem; Formation of HIV-1 elongation complex in the absence of HIV-1 Tat, organism-specific biosystem; Formation of RNA Pol II elongation complex, organism-specific biosystem; |
Function : | RNA binding; nucleotide binding; |
Products Types
◆ Recombinant Protein | ||
RDBP-7505M | Recombinant Mouse RDBP Protein, His (Fc)-Avi-tagged | +Inquiry |
RDBP-2235H | Recombinant Human RDBP, His-tagged | +Inquiry |
RDBP-14043M | Recombinant Mouse RDBP Protein | +Inquiry |
RDBP-29223TH | Recombinant Human RDBP, His-tagged | +Inquiry |
RDBP-3419H | Recombinant Human RD RNA Binding Protein, His-tagged | +Inquiry |
◆ Lysates | ||
RDBP-2440HCL | Recombinant Human RDBP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All RDBP Products
Required fields are marked with *
My Review for All RDBP Products
Required fields are marked with *
0
Inquiry Basket