Recombinant Full Length Human RGS2 Protein, T7-tagged

• Cat.No.: RGS2-29965TH
• Product Overview: Recombinant full length protein (Human) fused to T7-tag at the N-terminal end.

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 1-211 a.a.
• Description: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
• Conjugation: T7
• Tissue specificity: Expressed in acute myelogenous leukemia (AML) and in acute lymphoblastic leukemia (ALL).
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: 0.002% Sodium AzideConstituents: 10mM Tris, 0.1% Triton X-100, pH 8.0
• Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Contains 1 RGS domain.
• Full Length: Full L.

Gene Information

• Gene Name: RGS2 regulator of G-protein signaling 2, 24kDa [ Homo sapiens ]
• Official Symbol: RGS2
• Synonyms: RGS2; regulator of G-protein signaling 2, 24kDa; G0S8, regulator of G protein signalling 2, 24kD , regulator of G protein signalling 2, 24kDa; regulator of G-protein signaling 2
• Gene ID: 5997
• mRNA Refseq: NM_002923
• Protein Refseq: NP_002914
• MIM: 600861
• Uniprot ID: P41220
• Chromosome Location: 1q31
• Pathway: Calcium Regulation in the Cardiac Cell, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem; Signal Transduction, organism-specific biosystem
• Function: GTPase activator activity; calmodulin binding; signal transducer activity