"RGS2" Related Products


Recombinant Human RGS2, T7 -tagged

Cat.No.: RGS2-29965TH
Product Overview: Recombinant full length protein (Human) fused to T7-tag at the N-terminal end.
Description: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
Conjugation: T7
Source: E. coli
Tissue specificity: Expressed in acute myelogenous leukemia (AML) and in acute lymphoblastic leukemia (ALL).
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: 0.002% Sodium AzideConstituents: 10mM Tris, 0.1% Triton X-100, pH 8.0
Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities: Contains 1 RGS domain.
Gene Name: RGS2 regulator of G-protein signaling 2, 24kDa [ Homo sapiens ]
Official Symbol: RGS2
Synonyms: RGS2; regulator of G-protein signaling 2, 24kDa; G0S8, regulator of G protein signalling 2, 24kD , regulator of G protein signalling 2, 24kDa; regulator of G-protein signaling 2;
Gene ID: 5997
mRNA Refseq: NM_002923
Protein Refseq: NP_002914
MIM: 600861
Uniprot ID: P41220
Chromosome Location: 1q31
Pathway: Calcium Regulation in the Cardiac Cell, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
Function: GTPase activator activity; calmodulin binding; signal transducer activity;

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