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Recombinant Mouse Interleukin 11 Receptor, Alpha Chain 1

Cat. No.: Il11ra1-1759M
Description: Interleukin 11 receptor alpha (IL11RA) is a subunit of the interleukin 11 receptor that is expressed in hematopoietic and other organs. IL11RA is a functional target in bone metastasis and is considered as a candidate target in human osteosarcoma and provide leads for the development of novel imaging and therapeutic agents for the management of this malignant tumor.
Molecular Weight: The predicted molecular weight of Recombinant Mouse IL-11 Rα is Mr 65 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 70-80 kDa.
Source: NSO Cells.
State Of Matter: Lyophilized.
Purity: >97% by SDS Page and analyzed by silver stain.
Endotoxin: <0.1 ng per 1 µg as determined by the LAL method.
Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°Cto -70°C. After aseptic reconstitution, this protein may be stored at 2°Cto 8°Cfor one month or at -20°Cto -70°Cin a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name: Il11ra1 interleukin 11 receptor, alpha chain 1 [ Mus musculus ]
Synonyms: Il11ra1; interleukin 11 receptor, alpha chain 1; NR1; GP130; Il11ra; Il-11ra; Il11ra2; AI314697; locus 2; Il-11ra-alpha; OTTMUSP00000007071; OTTMUSP00000007072; OTTMUSP00000007073; OTTMUSP00000007074; interleukin 11 receptor, alpha chain 2
Gene ID: 16157
mRNA Refseq: NM_001163401
Protein Refseq: NP_001156873
UniProt ID: Q64385
Chromosome Location: 4 A5; 4 12.7 cM
Pathway: Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Jak-STAT signaling pathway
Function: cytokine receptor activity; interleukin-11 binding; interleukin-11 receptor activity; receptor activity

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