Recombinant Human RPS6
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Cat.No. : | RPS6-30769TH |
Product Overview : | Recombinant full length protein, corresponding to amino acids 1-249 of Human RPS6, plus N-terminal tag 29kDa. |
Description : | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. |
Source : | E. coli |
Form : | Lyophilised:Reconstitution with 163 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MKLNISFPAT GCQKLIEVDD ERKLRTFYEK RMATEVAADA LGEEWKGYVV RISGGNDKQG FPMKQGVLTH GRVRLLLSKG HSCYRPRRTG ERKRKSVRGC IVDANLSVLN LVIVKKGEKD IPGLTDTTVP RRLGPKRASR IRKLFNLSKE DDVRQYVVRK PLNKEGKKPR TKAPKIQRLV TPRVLQHKRR RIALKKQRTK KNKEEAAEYA KLLAKRMKEA KEKRQEQIAK RRRLSSLRAS TSKSESSQK |
Sequence Similarities : | Belongs to the ribosomal protein S6e family. |
Gene Name : | RPS6 ribosomal protein S6 [ Homo sapiens ] |
Official Symbol : | RPS6 |
Synonyms : | RPS6; ribosomal protein S6; 40S ribosomal protein S6; phosphoprotein NP33; S6; |
Gene ID : | 6194 |
mRNA Refseq : | NM_001010 |
Protein Refseq : | NP_001001 |
MIM : | 180460 |
Uniprot ID : | P62753 |
Chromosome Location : | 9p21 |
Pathway : | Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Cytoplasmic Ribosomal Proteins, organism-specific biosystem; Developmental Biology, organism-specific biosystem; |
Function : | protein binding; structural constituent of ribosome; |
◆ Recombinant Protein
RPS6-171 | Recombinant RPS6 Protein, GST-tagged | +Inquiry |
RPS6-14492M | Recombinant Mouse RPS6 Protein | +Inquiry |
RPS6-307H | Recombinant Human RPS6, GST-tagged | +Inquiry |
RPS6-5171R | Recombinant Rat RPS6 Protein | +Inquiry |
RPS6-6778C | Recombinant Chicken RPS6 | +Inquiry |
|
◆ Lysates
RPS6-567HCL | Recombinant Human RPS6 lysate | +Inquiry |
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RPS14 RPS27A RPS3 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA5 RPS6KA6 RPS6KB1 RPS6KB2 RPS6 RPS15 RPS17 RPS19 RPS2 RPS23 RPS27 RPS5 RPS7 RPS6KA4 RPS11 RPS20 RPS28 RPS29 RPS4X RPS6KC1 RPS8 RPS9 RPS24 RPS13 RPS26 RPS27L RPS18 RPS19BP1 RPS21 RPS25 RPS6KL1 RPS4Y1 RPS3A RPS15A RPS10 RPS12 Rps16 RPS17L
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