Recombinant Human RTN4IP1, His-tagged

• Cat.No.: RTN4IP1-27496TH
• Product Overview: Recombinant full length Human RTN4IP1 (amino acids 41-396) with N terminal His tag; 379 amino acids with tag, Predicted MWt 41.4 kDa.

Specification

• Description: This gene encodes a novel mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. The interaction of reticulon 4 with mitochondrial proteins may provide insight into the mechanisms for reticulon-induced inhibition of neurite growth.
• Protein length: 356 amino acids
• Conjugation: HIS
• Molecular Weight: 41.400kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Widely expressed in mitochondria-enriched tissues. Found in heart, muscle, kidney, liver, brain and placenta.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 20% Glycerol, 0.02% DTT
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

Gene Information

• Gene Name: RTN4IP1 reticulon 4 interacting protein 1 [ Homo sapiens ]
• Official Symbol: RTN4IP1
• Synonyms: RTN4IP1; reticulon 4 interacting protein 1; reticulon-4-interacting protein 1, mitochondrial; NIMP
• Gene ID: 84816
• mRNA Refseq: NM_032730
• Protein Refseq: NP_116119
• MIM: 610502
• Uniprot ID: Q8WWV3
• Chromosome Location: 6q21
• Function: nucleotide binding; oxidoreductase activity; zinc ion binding