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Recombinant Human SDHD

Cat.No. : SDHD-31390TH
Product Overview : Recombinant full length Human SDHD with a N terminal proprietary tag: predicted MW 43.56 kDa.
  • Specification
  • Gene Information
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Description : Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ.The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane.The subunit D protein is one of two integral membrane proteins anchoring the complex to the matrix side of the membrane.Mutations in SDHD have been linked to hereditary paraganglioma.
Protein length : 159 amino acids
Molecular Weight : 43.560kDa inclusive of tags
Source : Wheat germ
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MAVLWRLSAVCGALGGRALLLRTPVVRPAHISAFLQDRPI PEWCGVQHIHLSPSHHSGSKAASLHWTSERVVSVLLLGLL PAAYLNPCSAMDYSLAAALTLHGHWGLGQVVTDYVHGDAL QKAAKAGLLALSALTFAGLCYFNYHDVGICKAVAMLWKL
Sequence Similarities : Belongs to the CybS family.
Gene Name : SDHD succinate dehydrogenase complex, subunit D, integral membrane protein [ Homo sapiens ]
Official Symbol : SDHD
Synonyms : SDHD; succinate dehydrogenase complex, subunit D, integral membrane protein; PGL, PGL1; succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial;
Gene ID : 6392
mRNA Refseq : NM_003002
Protein Refseq : NP_002993
MIM : 602690
Uniprot ID : O14521
Chromosome Location : 11q23
Pathway : Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Citrate cycle (TCA cycle), organism-specific biosystem; Citrate cycle (TCA cycle), conserved biosystem; Citrate cycle, second carbon oxidation, 2-oxoglutarate =>
Function : electron carrier activity; heme binding; metal ion binding; succinate dehydrogenase activity; ubiquinone binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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