"SEPT6" Related Products

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Recombinant Human SEPT6, HIS-tagged

Cat.No.: SEPT6-30968TH
Product Overview: Recombinant full length Human SEPT6 with a N terminal His tag; 457 amino acids with the tag; predicted MWt of 52.1 kDa.
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.
Protein length: 434 amino acids
Conjugation: HIS
Molecular Weight: 52.100kDa inclusive of tags
Source: E. coli
Tissue specificity: Widely expressed.
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 0.03% DTT, 10% Glycerol, 0.58% Sodium chloride
Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMGSMAATDIARQVGEGCRTVPLAGHVGFDSLPDQLVNKSVSQGFCFNILCVGETGLGKSTLMDTLFNTKFEGEPATHTQPGVQLQSNTYDLQESNVRLKLTIVSTVGFGDQINKEDSYKPIVEFIDAQFEAYLQEELKIRRVLHTYHDSRIHVCLYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADAISKSELTKFKIKITSELVSNGVQIYQFPTDDESVAEINGTMNAHLPFAVIGSTEELKIGNKMMRARQYPWGTVQVENEAHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRCKLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVQRVKEKEAELKEAEKELHEKFDRLKKLHQDEKKKLEDKKKSLDDEVNAFKQRKTAAELPQSQGSQAGGSQTLKRDKEKKNNPWLCTE
Sequence Similarities: Belongs to the septin family.
Gene Name: SEPT6 septin 6 [ Homo sapiens ]
Official Symbol: SEPT6
Synonyms: SEPT6; septin 6; septin-6; KIAA0128; MGC16619; MGC20339; SEP2; SEPT2;
Gene ID: 23157
mRNA Refseq: NM_015129
Protein Refseq: NP_055944
MIM: 300683
Uniprot ID: Q14141
Chromosome Location: Xq24
Function: GTP binding; nucleotide binding; protein binding;

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