Native Human SERPINA7


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Native Human SERPINA7

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Cat.No. : SERPINA7-30623TH
Product Overview : Full length native Human Thyroxine Binding Globulin amino acids 21-415, purified from Human plasma. Predicted MWt 44kDa,
Description : There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3 -triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
Protein length : 395 amino acids
Molecular Weight : 44.000kDa
Form : Lyophilised:Use of phosphate buffer, pH >7.0 containing 0.15M NaCl is recommended.
Purity : by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 0.02M Ammonium bicarbonate. May contain traces of buffer salts.
Storage : Store at +4°C.
Gene Name : SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 [ Homo sapiens ]
Official Symbol : SERPINA7
Synonyms : SERPINA7; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7; serine (or cysteine) proteinase inhibitor, clade A (alpha 1 antiproteinase, antitrypsin), member 7 , TBG; thyroxine-binding globulin; alpha 1 antiproteinase; an
Gene ID : 6906
mRNA Refseq : NM_000354
Protein Refseq : NP_000345
Uniprot ID : P05543
Chromosome Location : Xq21-q22
Function : binding; hormone binding; serine-type endopeptidase inhibitor activity;

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