Recombinant Human SGK3

• Cat.No.: SGK3-27968TH
• Product Overview: Recombinant full length human inactive SGK3 with N-terminal proprietary tag expressed in a Baculovirus infected Sf9 cell expression system; amino acids 1-496, 82kDa.

Specification

• Description: This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Tissue specificity: Expressed in most tissues with highest levels in pancreas, kidney liver, heart and brain and lower levels in lung, placenta and skeletal muscle.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.Contains 1 AGC-kinase C-terminal domain.Contains 1 protein kinase domain.Contains 1 PX (phox homology) domain.

Gene Information

• Gene Name: SGK3 serum/glucocorticoid regulated kinase family, member 3 [ Homo sapiens ]
• Official Symbol: SGK3
• Synonyms: SGK3; serum/glucocorticoid regulated kinase family, member 3; serum/glucocorticoid regulated kinase like , SGK2, SGKL; serine/threonine-protein kinase Sgk3
• Gene ID: 23678
• mRNA Refseq: NM_001033578
• Protein Refseq: NP_001028750
• MIM: 607591
• Uniprot ID: Q96BR1
• Chromosome Location: 8q12
• Pathway: Insulin Signaling, organism-specific biosystem