Recombinant Human SLC22A3
Cat.No. : | SLC22A3-31412TH |
Product Overview : | Recombinant fragment of Human SLC22A3 with N terminal proprietary tag; Predicted MW 32.89 kDa. |
- Specification
- Gene Information
- Related Products
Description : | Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. |
Protein length : | 66 amino acids |
Molecular Weight : | 32.890kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | CQRYLLEAANDSASATSALSCADPL AAFPNRSAPLVPCRGGWRYAQAHST IVSEFDLVCVNAWMLD |
Sequence Similarities : | Belongs to the major facilitator superfamily. Organic cation transporter family. |
Gene Name : | SLC22A3 solute carrier family 22 (extraneuronal monoamine transporter), member 3 [ Homo sapiens ] |
Official Symbol : | SLC22A3 |
Synonyms : | SLC22A3; solute carrier family 22 (extraneuronal monoamine transporter), member 3; solute carrier family 22 member 3; EMT; OCT3; |
Gene ID : | 6581 |
mRNA Refseq : | NM_021977 |
Protein Refseq : | NP_068812 |
MIM : | 604842 |
Uniprot ID : | O75751 |
Chromosome Location : | 6q25.3 |
Pathway : | Organic cation transport, organism-specific biosystem; Organic cation/anion/zwitterion transport, organism-specific biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds, organism-specific biosystem; |
Function : | dopamine transmembrane transporter activity; ion transmembrane transporter activity; organic cation transmembrane transporter activity; protein binding; quaternary ammonium group transmembrane transporter activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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