"SLC9A3R1" Related Products


Recombinant Human SLC9A3R1

Cat.No.: SLC9A3R1-28223TH
Product Overview: Recombinant full length Human EBP50 with a proprietary tag: predicted molecular weight 65.90 kDa.
Description: This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.
Protein length: 358 amino acids
Molecular Weight: 65.900kDa inclusive of tags
Source: Wheat germ
Tissue specificity: Detected in liver, kidney, pancreas, prostate, spleen, small intestine and placenta, in particular in the syncytiotrophoblast.
Biological activity: Useful for Antibody Production and Protein Array
Form: Liquid
Purity: Proprietary Purification
Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.31% GlutathioneNote: Glutathione is reduced
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Contains 2 PDZ (DHR) domains.
Gene Name: SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 [ Homo sapiens ]
Official Symbol: SLC9A3R1
Synonyms: SLC9A3R1; solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1 , solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1; Na(+)/H(
Gene ID: 9368
mRNA Refseq: NM_004252
Protein Refseq: NP_004243
MIM: 604990
Uniprot ID: O14745
Chromosome Location: 17q25.1
Pathway: PDGFR-beta signaling pathway, organism-specific biosystem; Thromboxane A2 receptor signaling, organism-specific biosystem;
Function: PDZ domain binding; beta-2 adrenergic receptor binding; beta-catenin binding; chloride channel regulator activity; dopamine receptor binding;

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