"SNX1" Related Products

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Recombinant Human SNX1, His-tagged

Cat.No.: SNX1-30609TH
Product Overview: Recombinant fragment corresponding to amino acids 146-522 of Human SNX1 with an N terminal His tag; 415 amino acids with tag, Predicted MWt 48 kDa.
Description: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
Protein length: 377 amino acids
Conjugation: HIS
Molecular Weight: 48.000kDa inclusive of tags
Source: E. coli
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGGSMTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEAFLPEAKAIS
Sequence Similarities: Belongs to the sorting nexin family.Contains 1 BAR domain.Contains 1 PX (phox homology) domain.
Gene Name: SNX1 sorting nexin 1 [ Homo sapiens ]
Official Symbol: SNX1
Synonyms: SNX1; sorting nexin 1; sorting nexin-1; HsT17379; MGC8664; SNX1A; Vps5;
Gene ID: 6642
mRNA Refseq: NM_001242933
Protein Refseq: NP_001229862
MIM: 601272
Uniprot ID: Q13596
Chromosome Location: 15q22.31
Pathway: TGF-beta Receptor Signaling Pathway, organism-specific biosystem;
Function: lipid binding; phosphatidylinositol binding; protein binding; protein transporter activity;

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