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Recombinant Human SRGN, His-tagged

Cat.No. : SRGN-31396TH
Product Overview : Recombinant full length mature Human SRGN (aa 28-158) with N terminal His tag; 156aa, 17.4kDa inclusive of tag.
  • Specification
  • Gene Information
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Description : This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene.
Protein length : 131 amino acids
Conjugation : HIS
Molecular Weight : 17.400kDa
Source : E. coli
Form : Liquid
Purity : >90% by SDS-PAGE
Storage buffer : pH: 8.00Constituents:0.32% Tris HCl, 0.03% DTT, 0.88% Sodium chloride, 10% Glycerol
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MGSHMYPTRR ARYQWVRCNP DSNSANCLEE KGPMFELLPG ESNKIPRLRT DLFPKTRIQD LNRIFPLSED YSGSGFGSGS GSGSGSGSGF LTEMEQDYQL VDESDAFHDN LRSLDRNLPS DSQDLGQHGL EEDFML
Sequence Similarities : Belongs to the serglycin family.
Gene Name : SRGN serglycin [ Homo sapiens ]
Official Symbol : SRGN
Synonyms : SRGN; serglycin; PRG, PRG1, proteoglycan 1, secretory granule; PPG; serglycin proteoglycan;
Gene ID : 5552
mRNA Refseq : NM_002727
Protein Refseq : NP_002718
MIM : 177040
Uniprot ID : P10124
Chromosome Location : 10q22.1
Pathway : Hemostasis, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; Platelet degranulation, organism-specific biosystem; Response to elevated platelet cytosolic Ca2+, organism-specific biosystem;
Function : collagen binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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