Recombinant Human TALDO1, His-tagged

• Cat.No.: TALDO1-31154TH
• Product Overview: Recombinant full length Human Transaldolase 1 with an N terminal His tag; 357 amino acids including tag, predicted MWt 39.7kDa. (

Specification

• Description: Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.
• Protein length: 337 amino acids
• Conjugation: HIS
• Molecular Weight: 39.700kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMSSSP VKRQRMESALDQLKQFTTVVADTGD FHAIDEYKPQDATTNPSLILAAAQM PAYQELVEEAIAYGRKLGGSQEDQI KNAIDKLFVLFGAEILKKIPGRVST EVDARLSFDKDAMVARARRLIELYK EAGISKDRILIKLSSTWEGIQAGKE LEEQHGIHCNMTLLFSFAQAVACAE AGVTLISPFVGRILDWHVANTDKKS YEPLEDPGVKSVTKIYNYYKKFSYK TIVMGASFRNTGEIKALAGCDFLTI SPKLLGELLQDNAKLVPVLSAKAAQ ASDLEKIHLDEKSFRWLHNEDQMAV EKLSDGIRKFAADAVKLERMLTERM FNAENGK

Gene Information

• Gene Name: TALDO1 transaldolase 1 [ Homo sapiens ]
• Official Symbol: TALDO1
• Synonyms: TALDO1; transaldolase 1; transaldolase
• Gene ID: 6888
• mRNA Refseq: NM_006755
• Protein Refseq: NP_006746
• MIM: 602063
• Uniprot ID: P37837
• Chromosome Location: 11p15.5-p15.4
• Pathway: Insulin effects increased synthesis of Xylulose-5-Phosphate, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem
• Function: monosaccharide binding; sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity; transferase activity