Recombinant Human TARS, His-tagged

• Cat.No.: TARS-30151TH
• Product Overview: Recombinant Full Length Human TARS is a glycosylated, polypeptide chain produced in SF9 and expressed with a 6xHis tag, 83 kDa.

Specification

• Description: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution.
• Conjugation: HIS
• Biological activity: TARS-30151THbinds IgG human auto antibodies and is reactive with Polymyositis sera.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 200mM Sodium chloride, 20mM HEPES, pH 8
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the class-II aminoacyl-tRNA synthetase family.

Gene Information

• Gene Name: TARS threonyl-tRNA synthetase [ Homo sapiens ]
• Official Symbol: TARS
• Synonyms: TARS; threonyl-tRNA synthetase; threonyl-tRNA synthetase, cytoplasmic; threonine tRNA ligase 1; cytoplasmic
• Gene ID: 6897
• mRNA Refseq: NM_152295
• Protein Refseq: NP_689508
• MIM: 187790
• Uniprot ID: P26639
• Chromosome Location: 5p13.2
• Pathway: Aminoacyl-tRNA biosynthesis, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, conserved biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, conserved biosystem; Cytosolic tRNA aminoacylation, organism-specific biosystem
• Function: ATP binding; ligase activity; nucleotide binding; protein homodimerization activity; threonine-tRNA ligase activity