Native Human TF

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Cat.No. :	TF-31156TH
Product Overview :	Full length native Human Transferrin purified from human plasma.
Description :	This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum.
Tissue specificity :	Expressed by the liver and secreted in plasma.
Biological activity :	TF-31156TH has an iron binding capacity of 1.2 to 1.6ug/mg.
Form :	Lyophilised:Reconstitute with 5.62ml distilled water.
Purity :	>95% by SDS-PAGE
Storage buffer :	Preservative: NoneConstituents: 10mM PBS, pH 7.4
Storage :	Store at -20°C. Stable for 12 months at -20°C
Sequence Similarities :	Belongs to the transferrin family.Contains 2 transferrin-like domains.

Gene Name :	TF transferrin [ Homo sapiens ]
Official Symbol :	TF
Synonyms :	TF; transferrin; serotransferrin; PRO1557; PRO2086;
Gene ID :	7018
mRNA Refseq :	NM_001063
Protein Refseq :	NP_001054
MIM :	190000
Uniprot ID :	P02787
Chromosome Location :	3q21
Pathway :	EPHB forward signaling, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; Hemostasis, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Mineral absorption, organism-specific biosystem;
Function :	ferric iron binding; metal ion binding; protein binding; ubiquitin protein ligase binding;