Recombinant Human TIE1

• Cat.No.: TIE1-30626TH
• Product Overview: Recombinant fusion protein (Human).Recombinant human soluble TIE 1 was fused with the Fc part of human IgG1. The soluble receptor protein consists of the full extracellular domain (Met1-Glu749).The recombinant mature TIE-1/Fc is a disulfide-linked homodim

Specification

• Description: Tyrosine kinase with immunoglobulin-like and EGF-like domains 1 also known as TIE1 is an angiopoietin receptor which in humans is encoded by the TIE1 gene.
• Tissue specificity: Specifically expressed in developing vascular endothelial cells.
• Form: Lyophilised:The protein can be reconstituted in ddH2O or PBS to a concentration of 100μg/ml.
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: PBS
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. Tie subfamily.Contains 3 EGF-like domains.Contains 3 fibronectin type-III domains.Contains 2 Ig-like C2-type (immunoglobulin-like) domains.Contains 1 protein kinase domain.

Gene Information

• Gene Name: TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 [ Homo sapiens ]
• Official Symbol: TIE1
• Synonyms: TIE1; tyrosine kinase with immunoglobulin-like and EGF-like domains 1; TIE, tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1; tyrosine-protein kinase receptor Tie-1; JTK14
• Gene ID: 7075
• mRNA Refseq: NM_005424
• Protein Refseq: NP_005415
• MIM: 600222
• Uniprot ID: P35590
• Chromosome Location: 1p34-p33
• Function: ATP binding; nucleotide binding; protein binding; protein tyrosine kinase activity; receptor activity