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Recombinant Human TKT, His-tagged

Cat.No. : TKT-30354TH
Product Overview : Recombinant fragment, corresponding to amino acids 29-540 of Human Transketolase with an N terminal His tag. Predicted MWt: 57 kDa;
  • Specification
  • Gene Information
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Description : This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Conjugation : HIS
Source : E. coli
Form : Lyophilised:Reconstitute with 145 μl aqua dest.
Storage buffer : Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : ATTAAGSGHPTSCCSAAEIMAVLFFHTGKYFDKASYRVYC LLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQ SDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKA FGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMA EQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPS LPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTK NSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTV PFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSI GEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVE LAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSK DDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTI KPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSA VVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQA VRGLITKA
Sequence Similarities : Belongs to the transketolase family.
Gene Name : TKT transketolase [ Homo sapiens ]
Official Symbol : TKT
Synonyms : TKT; transketolase; Wernicke Korsakoff syndrome;
Gene ID : 7086
mRNA Refseq : NM_001064
Protein Refseq : NP_001055
MIM : 606781
Uniprot ID : P29401
Chromosome Location : 3p14.3
Pathway : Insulin effects increased synthesis of Xylulose-5-Phosphate, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem;
Function : magnesium ion binding; monosaccharide binding; thiamine pyrophosphate binding; transferase activity; transketolase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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