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Recombinant Human TKT, His-tagged

Cat.No. : TKT-30354TH
Product Overview : Recombinant fragment, corresponding to amino acids 29-540 of Human Transketolase with an N terminal His tag. Predicted MWt: 57 kDa;
Description : This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Conjugation : HIS
Source : E. coli
Form : Lyophilised:Reconstitute with 145 μl aqua dest.
Storage buffer : Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : ATTAAGSGHPTSCCSAAEIMAVLFFHTGKYFDKASYRVYC LLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQ SDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKA FGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMA EQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPS LPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTK NSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTV PFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSI GEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVE LAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSK DDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTI KPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSA VVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQA VRGLITKA
Sequence Similarities : Belongs to the transketolase family.
Gene Name : TKT transketolase [ Homo sapiens ]
Official Symbol : TKT
Synonyms : TKT; transketolase; Wernicke Korsakoff syndrome;
Gene ID : 7086
mRNA Refseq : NM_001064
Protein Refseq : NP_001055
MIM : 606781
Uniprot ID : P29401
Chromosome Location : 3p14.3
Pathway : Insulin effects increased synthesis of Xylulose-5-Phosphate, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem;
Function : magnesium ion binding; monosaccharide binding; thiamine pyrophosphate binding; transferase activity; transketolase activity;

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