Recombinant Human TPI1

• Cat.No.: TPI1-31613TH
• Product Overview: Recombinant full length Human Triosephosphate isomerase, expressed in Saccharomyces cerevisiae, amino acids 1-249. MW 26.6 kDa.

Specification

• Description: This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 30% Glycerol, 0.5% Triton-X-100, 50mM HEPES, 30mM Glutathione, 100mM Sodium chloride, 1mM DTT, pH 7.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequences of amino acids: MAPSRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEV VCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGE ISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAH ALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADN VKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGW LKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGF LVGGASLKPEFVDIINAKQ

Gene Information

• Gene Name: TPI1 triosephosphate isomerase 1 [ Homo sapiens ]
• Official Symbol: TPI1
• Synonyms: TPI1; triosephosphate isomerase 1; triosephosphate isomerase
• Gene ID: 7167
• mRNA Refseq: NM_000365
• Protein Refseq: NP_000356
• Uniprot ID: P60174
• Chromosome Location: 12p13.31
• Pathway: Fatty Acid Beta Oxidation, organism-specific biosystem; Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; Gluconeogenesis, organism-specific biosystem; Gluconeogenesis, oxaloacetate =>
• Function: isomerase activity; triose-phosphate isomerase activity; triose-phosphate isomerase activity; triose-phosphate isomerase activity