Recombinant Human TRADD, His-tagged
Cat.No. : | TRADD-29977TH |
Product Overview : | Recombinant full length protein, corresponding to amino acids 1-150 of Human TRADD with an N terminal His tag; Predicted MWt 17 kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. |
Conjugation : | HIS |
Source : | E. coli |
Tissue specificity : | Found in all examined tissues. |
Form : | Lyophilised:Reconstitute with 113 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVA VYRALQAALAALLAQDPSPVPTLPGPPFPSQGRGHRRL KRVGGSVRGLRAARAPLLPEQWESRLVEAEDLRPLALL CPAGRLPRRLVCPGHTPPFLCFEVPLFCQPSFGA |
Sequence Similarities : | Contains 1 death domain. |
Gene Name : | TRADD TNFRSF1A-associated via death domain [ Homo sapiens ] |
Official Symbol : | TRADD |
Synonyms : | TRADD; TNFRSF1A-associated via death domain; tumor necrosis factor receptor type 1-associated DEATH domain protein; Hs.89862; |
Gene ID : | 8717 |
mRNA Refseq : | NM_003789 |
Protein Refseq : | NP_003780 |
MIM : | 603500 |
Uniprot ID : | Q15628 |
Chromosome Location : | 16q22 |
Pathway : | Activation of Pro-Caspase 8, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; |
Function : | binding, bridging; death domain binding; identical protein binding; kinase binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
TRADD-3383H | Recombinant Human TRADD protein, His-tagged | +Inquiry |
Tradd-1415M | Recombinant Mouse Tradd protein, His & T7-tagged | +Inquiry |
TRADD-6657H | Recombinant Human TRADD Protein (Met61-Leu297), N-His tagged | +Inquiry |
TRADD-4420H | Recombinant Human TRADD protein, GST-tagged | +Inquiry |
TRADD-3384H | Recombinant Human TRADD protein, His-tagged | +Inquiry |
◆ Lysates | ||
TRADD-826HCL | Recombinant Human TRADD 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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