Recombinant Human TUBG1, His-tagged

• Cat.No.: TUBG1-28973TH
• Product Overview: Recombinant full length Human gamma Tubulin with an N terminal His tag; 471aa, 53.3kDa.

Specification

• Description: This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7.
• Protein length: 451 amino acids
• Conjugation: HIS
• Molecular Weight: 53.300kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 6% Urea, 5% Glycerol
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMPREIITLQLGQCGNQIGFE FWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHY IPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGA GNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHS IAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSD VVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHI QNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASL IPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQP KNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRI RERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMAN HTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDE MDTSREIVQQLIDEYHAATRPDYISWGTQEQ

Gene Information

• Gene Name: TUBG1 tubulin, gamma 1 [ Homo sapiens ]
• Official Symbol: TUBG1
• Synonyms: TUBG1; tubulin, gamma 1; TUBG, tubulin, gamma polypeptide; tubulin gamma-1 chain; TUBGCP1
• Gene ID: 7283
• mRNA Refseq: NM_001070
• Protein Refseq: NP_001061
• MIM: 191135
• Uniprot ID: P23258
• Chromosome Location: 17q21.31
• Pathway: Cell Cycle, Mitotic, organism-specific biosystem; Centrosome maturation, organism-specific biosystem; G2/M Transition, organism-specific biosystem; Loss of Nlp from mitotic centrosomes, organism-specific biosystem; Loss of proteins required for interphase microtubule organization??from the centrosome, organism-specific biosystem
• Function: GTP binding; GTPase activity; nucleotide binding; protein binding; structural constituent of cytoskeleton