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Recombinant Human YES1

Cat.No.: YES1-30137TH
Product Overview: Recombinant full length Human Yes1 with N terminal proprietary tag; MWt 91kDa.
Description: This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22.
Protein length: 542 amino acids
Molecular Weight: 91.000kDa inclusive of tags
Source: Baculovirus
Biological activity: The Specific activity was determined to be 185 nmol/min/mg.
Form: Liquid
Purity: Densitometry
Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.Contains 1 protein kinase domain.Contains 1 SH2 domain.Contains 1 SH3 domain.
Gene Name: YES1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 [ Homo sapiens ]
Official Symbol: YES1
Synonyms: YES1; v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1; tyrosine-protein kinase Yes; c yes; HsT441; Yes;
Gene ID: 7525
mRNA Refseq: NM_005433
Protein Refseq: NP_005424
MIM: 164880
Uniprot ID: P07947
Chromosome Location: 18p11.31-p11.21
Pathway: Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Alpha-synuclein signaling, organism-specific biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem;
Function: ATP binding; ion channel binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein tyrosine kinase activity;

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