Recombinant Human Guanidinoacetate N-methyltransferase, His-tagged
Cat.No. : | GAMT-483H |
Product Overview : | Recombinant human GAMT, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW= 28.4 kDa (256aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | GAMT-483H |
Description : | Guanidinoacetate N-methyltransferase isoform a, also known as GAMT is a methyltansferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl domor. This enzyme participates in the two-step synthesis of the compound creatine from the protein building blocks glycine, arginine, and methionine. It is involved in providing energy for muscle contraction, and is also important in nervous system functioning. Also GAMT is active in the liver, pancreas, and kidneys. |
Source : | E.coli. |
Amino Acid Sequence : | MGSSHHHHHH SSGLVPRGSH MSAPSATPIF APGENCSPAW GAAPAAYDAA DTHLRILGKP VMERWETPYM HALAAAASSK GGRVLEVGFG MAIAASKVQE APIDEHWIIE CNDGVFQRLR DWAPRQTHKV IPLKGLWEDV APTLPDGHFD GILYDTYPLS EETWHTHQFN FIKNHAFRLL KPGGVLTYCN LTSWGELMKS KYSDITIMFE ETQVPALLEA GFRRENIRTE VMALVPPADC RYYAFPQMIT PLVTKG |
Form : | Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol. |
Purity : | > 95% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | GAMT guanidinoacetate N-methyltransferase [ Homo sapiens ] |
Synonyms : | GAMT; guanidinoacetate N-methyltransferase; PIG2; TP53I2; EC 2.1.1.2 |
Gene ID : | 2593 |
mRNA Refseq : | NM_000156 |
Protein Refseq : | NP_000147 |
MIM : | 601240 |
UniProt ID : | Q14353 |
Chromosome Location : | 19p13.3 |
Pathway : | Arginine and proline metabolism; Glycine, serine and threonine metabolism; Metabolic pathways |
Function : | guanidinoacetate N-methyltransferase activity; methyltransferase activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
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Gamt-3147M | Recombinant Mouse Gamt Protein, Myc/DDK-tagged | +Inquiry |
GAMT-3462M | Recombinant Mouse GAMT Protein, His (Fc)-Avi-tagged | +Inquiry |
GAMT-3009H | Recombinant Human GAMT Protein, His (Fc)-Avi-tagged | +Inquiry |
GAMT-1250H | Recombinant Human GAMT Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
GAMT-684HCL | Recombinant Human GAMT cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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