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Recombinant Human Ghrelin/Obestatin Prepropeptide

Cat. No.: GHRL-179H
Product Overview: Recombinant human Ghrelin protein was expressed inE.coliand purified by using conventional chromatography techniques. MW = 12.8 kDa (115aa).
Description: Ghrelin, also known as Obestatin, is the ligand for growth hormone secretagogue receptor type 1 (GHSR). It induces the release of growth hormone from the pituitary and involved in growth regulation. This protein has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Ghrelin plays a significant role in neurotrophy, particularly in the hippocampus, and is essential for cognitive adaptation to changing environments and the process of learning.
Source: E.coli.
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSSFLSPEH QRVQQRKESK KPPAKLQPRA LAGWLRPEDG GQAEGAEDEM EVRFNAPFDV GIKLSGVQYQ QHSQALGKFL QDILWEEAKE APADK
Form: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol.
Purity: > 90% by SDS – PAGE.
Concentration: 1 mg/ml (determined by Bradford assay).
Endotoxin Level: < 1.0 EU per 1 μg of protein (determined by LAL method).
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: GHRL ghrelin/obestatin prepropeptide [ Homo sapiens ]
Synonyms: GHRL; ghrelin/obestatin prepropeptide; MTLRP; obestatin; ghrelin/obestatin; OTTHUMP00000207794; OTTHUMP00000207795; OTTHUMP00000207796; OTTHUMP00000207798; motilin-related peptide; ghrelin/obestatin preprohormone; ghrelin, growth hormone secretagogue receptor ligand; ghrelin; Appetite-regulating hormone; M46 protein; Growth hormone secretagogue; Growth hormone-releasing peptide; Ghrelin-27; Ghrelin-28
Gene ID: 51738
mRNA Refseq: NM_001134941
Protein Refseq: NP_001128413
MIM: 605353
UniProt ID: Q9UBU3
Chromosome Location: 3p26-p25
Pathway: Neuroactive ligand-receptor interaction
Function: ghrelin receptor binding; growth hormone-releasing hormone activity; protein tyrosine kinase activator activity

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