Recombinant Human Ghrelin/Obestatin Prepropeptide

• Cat.No.: GHRL-179H
• Product Overview: Recombinant human Ghrelin protein was expressed inE.coliand purified by using conventional chromatography techniques. MW = 12.8 kDa (115aa).

Specification

• Cat. No.: GHRL-179H
• Description: Ghrelin, also known as Obestatin, is the ligand for growth hormone secretagogue receptor type 1 (GHSR). It induces the release of growth hormone from the pituitary and involved in growth regulation. This protein has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Ghrelin plays a significant role in neurotrophy, particularly in the hippocampus, and is essential for cognitive adaptation to changing environments and the process of learning.
• Source: E.coli.
• Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSSFLSPEH QRVQQRKESK KPPAKLQPRA LAGWLRPEDG GQAEGAEDEM EVRFNAPFDV GIKLSGVQYQ QHSQALGKFL QDILWEEAKE APADK
• Form: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol.
• Purity: > 90% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Endotoxin Level: < 1.0 EU per 1 μg of protein (determined by LAL method).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: GHRL ghrelin/obestatin prepropeptide [ Homo sapiens ]
• Synonyms: GHRL; ghrelin/obestatin prepropeptide; MTLRP; obestatin; ghrelin/obestatin; OTTHUMP00000207794; OTTHUMP00000207795; OTTHUMP00000207796; OTTHUMP00000207798; motilin-related peptide; ghrelin/obestatin preprohormone; ghrelin, growth hormone secretagogue receptor ligand; ghrelin; Appetite-regulating hormone; M46 protein; Growth hormone secretagogue; Growth hormone-releasing peptide; Ghrelin-27; Ghrelin-28
• Gene ID: 51738
• mRNA Refseq: NM_001134941
• Protein Refseq: NP_001128413
• MIM: 605353
• UniProt ID: Q9UBU3
• Chromosome Location: 3p26-p25
• Pathway: Neuroactive ligand-receptor interaction
• Function: ghrelin receptor binding; growth hormone-releasing hormone activity; protein tyrosine kinase activator activity