Recombinant Human HDGF


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Recombinant Human HDGF

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Cat. No. : HDGF-361H
Product Overview : Recombinant human HDGF was expressed inE.coliand purified by using conventional chromatography techniques. MW = 11.5 kDa (100aa).
Description : Hepatoma-derived growth factor isoform a, also known as HDGF, belongs to the hepatoma-derived growth factor family. HDGF was originally identified as a secreted mitogen from the human hepatoma cell line Huh-7. This nuclear targeted vascular smooth muscle cell mitogen is a heparin-binding protein that is highly expressed in tumor cells where it stimulates proliferation. HDGF is also reported to be involved in organ development and lung remodeling after injury by promoting proliferation of lung epithelial cells.
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer (pH7.5) containing 1mM DTT, 10% glycerol, 1mM EDTA
Purity : > 95% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
PDB rendering based on 1ri0. :

Gene Name : HDGF hepatoma-derived growth factor (high-mobility group protein 1-like) [ Homo sapiens ]
Synonyms : HDGF; hepatoma-derived growth factor (high-mobility group protein 1-like); HMG1L2; FLJ96580; DKFZp686J1764; Hepatoma-derived growth factor; High-mobility group protein 1-like 2; HMG-1L2; OTTHUMP00000038721
Gene ID : 3068
mRNA Refseq : NM_001126050
Protein Refseq : NP_001119522
MIM : 600339
UniProt ID : P51858
Chromosome Location : 1q21-q23
Function : DNA binding; growth factor activity; heparin binding; nucleotide binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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