| Cat. No.: | cka2-204Z |
| Product Overview: | Recombinant Zea Mays Casein Kinase 2 alpha is a non-glycosylated polypeptide having a molecular mass of 39.2 kDa. Casein Kinase 2 is purified by proprietary chromatographic techniques. It is produced inE.Coli. |
| Description: | The Casein kinase 2 (EC2.7.11.1) is a serine/threonine-selective protein kinasethat is a tetramer of two alpha subunits and two beta subunits. The alpha subunits have the catalytic kinase domain. Casein kinase 2 has been implicated in cell cyclecontrol, DNA repair, regulation of the circadian rhythmand other cellular processes. Casein kinase 2 activity has been reported to be activated following Wnt signaling pathwayactivation. A Pertussis toxin-sensitive G proteinand Disheveled appear to be an intermediary between Wnt-mediated activation of the Frizzled receptor and activation of casein kinase 2. |
| Source: | Escherichia Coli. |
| Formulation: | CK2a is supplied in 50% glycerol. |
| Purity: | Greater than 99% as determined by SDS-PAGE. |
| Unit Definition: | No protease activity detectable, specific activity > 1U/mg (1U = 1µmol/min at 37°C) using the synthetic peptide RRRDDDSDDD. |
| Storage: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Gene Name: | cka2 CK2 protein kinase alpha 2 [ Zea mays ] |
| Synonyms: | cka2; CK2 protein kinase alpha 2; CK2; CK2 alpha subunit; PCO082342; PCO082342_ov; casein kinase II alpha subunit; casein kinase2 subunit alpha; casein protein kinase subunit alpha; ck2a2 |
| Gene ID: | 542460 |
| mRNA Refseq: | NM_001112016 |
| Protein Refseq: | NP_001105486 |
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