Species : |
Zea Mays |
Source : |
E.coli |
Tag : |
Non |
Description : |
The Casein kinase 2 (EC2.7.11.1) is a serine/threonine-selective protein kinasethat is a tetramer of two alpha subunits and two beta subunits. The alpha subunits have the catalytic kinase domain. Casein kinase 2 has been implicated in cell cyclecontrol, DNA repair, regulation of the circadian rhythmand other cellular processes. Casein kinase 2 activity has been reported to be activated following Wnt signaling pathwayactivation. A Pertussis toxin-sensitive G proteinand Disheveled appear to be an intermediary between Wnt-mediated activation of the Frizzled receptor and activation of casein kinase 2. |
Formulation : |
CK2a is supplied in 50% glycerol. |
Purity : |
Greater than 99% as determined by SDS-PAGE. |
Unit Definition : |
No protease activity detectable, specific activity > 1U/mg (1U = 1µmol/min at 37°C) using the synthetic peptide RRRDDDSDDD. |
Storage : |
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. |