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Recombinant Human Annexin A2, His-tagged

Cat. No.: ANXA2-1845H
Product Overview: Recombinant human Annexin A2 protein produced inE.coliwas recombined with His tag at the N Terminus. It was purified by using conventional chromatography techniques, 42.8 kDa (376aa).
Description: Annexin A2 belongs to a family of calcium-dependent membrane and phospholipid binding proteins. It plays a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption.
Source: E.coli.
Purity: > 95% by SDS - PAGE.
Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl.
Concentration: 0.5 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMST VHEILCKLSL EGDHSTPPSA YGSVKAYTNF DAERDALNIE TAIKTKGVDEVTIVNILTNR SNAQRQDIAF AYQRRTKKEL ASALKSALSG HLETVILGLL KTPAQYDASE LKASMKGLGT DEDSLIEIIC SRTNQELQEINRVYKEMYKT DLEKDIISDT SGDFRKLMVA LAKGRRAEDG SVIDYELIDQ DARDLYDAGV KRKGTDVPKW ISIMTERSVP HLQKVFDRYKSYSPYDMLES IRKEVKGDLE NAFLNLVQCI QNKPLYFADR LYDSMKGKGT RDKVLIRIMV SRSEVDMLKI RSEFKRKYGK SLYYYIQQDTKGDYQKALLY LCGGDD.
Stability: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: ANXA2 annexin A2 [ Homo sapiens ]
Synonyms: annexin A2; P36; ANX2; LIP2; LPC2; CAL1H; LPC2D; ANX2L4; PAP-IV; ANXA2; annexin-2; protein I; annexin II; lipocortin II; chromobindin 8; chromobindin-8; calpactin I heavy chain; calpactin-1 heavy chain; calpactin I heavy polypeptide; placental anticoagulant protein IV; Annexin II; Lipocortin II; Placental anticoagulant protein IV; Chromobindin-8; Annexin-2; Protein I; Calpactin I heavy chain
Gene ID: 302
mRNA Refseq: NM_001002857.1
Protein Refseq: NP_001002857.1
MIM: 151740
UniProt ID: P07355
Chromosome Location: 15q21-q22
Function: Rab GTPase binding; calcium ion binding; calcium-dependent phospholipid binding; cytoskeletal protein binding; phosphatidylinositol-4,5-bisphosphate binding; phospholipase inhibitor activity; protein binding

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