| Cat. No.: | Ifna1-70R |
| Product Overview: | Recombinant Rat Interferon Alpha 1, produced by transfectedinsect cells (Sf9), was 19.0 kDa. |
| Description: | Interferon alpha-1/13 is a protein that in humans is encoded by the IFNA1 gene. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes. |
| Source: | Insect cells (Sf9). |
| Purity: | > 95% by HPLC analysis. |
| Biological Activity: | Fully biologically active when compared to standards. Specific activity of 2 x 108 units/mg, as determined by cytopathic effect inhibition assay using rat cells challenged with VSV. |
| Handling And Storage: | Purified Rat IFN Alpha 1 factor is provided lyophilized from Tris buffer with 200 ug/mL rat serum albumin. Store lyophilized, at -20°C. Upon reconstitution with 100 uL distilled water or buffer (5 mM Tris, 150 mM NaCl, pH 7.0), further dilute in buffered solutions. Store small aliquots at -20°C for long-term storage, at high concentration. |
| Gene Name: | Ifna1 interferon-alpha 1 [ Rattus norvegicus ] |
| Synonyms: | Ifna1; interferon-alpha 1; IFN-alpha1; interferon alpha 1 |
| Gene ID: | 298210 |
| mRNA Refseq: | NM_001014786 |
| Protein Refseq: | NP_001014786 |
| UniProt ID: | P05011 |
| Chromosome Location: | 5q32 |
| Pathway: | Antigen processing and presentation; Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; RIG-I-like receptor signaling pathway; Regulation of autophagy; Toll-like receptor signaling pathway |
| Function: | cytokine activity; cytokine receptor binding |
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