"DHPS" Related Products

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Recombinant Human Deoxyhypusine Synthase, His-tagged

Cat. No.: DHPS-568H
Product Overview: Recombinant Human DHPS protein was expressed inE.coliwith His tag and purified by conventional chromatography techniques. MW=43.1 kDa (389aa).
Description: DHPS, which belongs to the deoxyhypusine synthase family of proteins, is important for the first step in the hypusine biosynthesis pathway. This protein catalyzes the NAD-dependent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the EIF5A precursor protein to form the intermediate deoxyhypusine residue.
Source: E.coli.
Sequences: MGSSHHHHHH SSGLVPRGSH MEGSLEREAP AGALAAVLKH SSTLPPESTQ VRGYDFNRGV NYRALLEAFG TTGFQATNFG RAVQQVNAMI EKKLEPLSQD EDQHADLTQS RRPLTSCTIF LGYTSNLISS GIRETIRYLV QHNMVDVLVT TAGGVEEDLI KCLAPTYLGE FSLRGKELRE NGINRIGNLL VPNENYCKFE DWLMPILDQM VMEQNTEGVK WTPSKMIARL GKEINNPESV YYWAQKNHIP VFSPALTDGS LGDMIFFHSY KNPGLVLDIV EDLRLINTQA IFAKCTGMII LGGGVVKHHI ANANLMRNGA DYAVYINTAQ EFDGSDSGAR PDEAVSWGKI RVDAQPVKVY ADASLVFPLL VAETFAQKMD AFMHEKNED.
Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl.
Purity: > 95% by SDS – PAGE.
Concentration: 1.0 mg/ml (determined by Bradford assay).
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: DHPS deoxyhypusine synthase [ Homo sapiens ]
Synonyms: DHPS; deoxyhypusine synthase; MIG13; migration-inducing gene 13; DHS; EC 2.5.1.46
Gene ID: 1725
mRNA Refseq: NM_001930
Protein Refseq: NP_001921
MIM: 600944
UniProt ID: P49366
Chromosome Location: 19p13.2-p13.1
Pathway: Metabolism of proteins
Function: deoxyhypusine synthase activity; protein binding; transferase activity

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