Recombinant Rat Apoptotic Peptidase Activating Factor 1, His-tagged

• Cat.No.: Apaf1-2062R
• Product Overview: Recombinant rat full-length Apaf-1 produced inE. coliis fused with a C-terminal His-tag.

Specification

• Cat. No.: Apaf1-2062R
• Description: Apoptotic protease activating factor 1, also known as APAF1, is a human homolog of C. elegans CED-4 gene. APAF-1 and CED-4 homologs were found in all currently sequenced animal genomes.
• Source/Host: E. coli.
• Purity: ~95% (SDS-PAGE).
• Formulation: Liquid. In 20mM TRIS-HCl, pH 8.5.
• Concentration: 0.25mg/ml.
• Short Term Storage: -20°C.
• Long Term Storage: -80°C.
• Use/Stability: Stability at -20°C: 1-2 weeks.
• Handling: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Apaf1 apoptotic peptidase activating factor 1 [ Rattus norvegicus ]
• Synonyms: apoptotic peptidase activating factor 1; Apaf1; apoptotic protease-activating factor 1; apaf-1
• Gene ID: 78963
• mRNA Refseq: NM_023979
• Protein Refseq: NP_076469
• UniProt ID: Q9EPV5
• Chromosome Location: 7q13
• Pathway: Alzheimer"s disease; Amyotrophic lateral sclerosis (ALS); Apoptosis; Huntington"s disease; Parkinson"s disease; Small cell lung cancer; p53 signaling pathway
• Function: apoptotic protease activator activity; ATP binding; identical protein binding; nucleotide binding; peptidase activity; protein binding