Recombinant Human TNFSF9, FLAG-tagged

• Cat.No.: TNFSF9-2075H
• Product Overview: Recombinant Human TNFSF9 is produced inHEK 293 Cells.The extracellular domain of human CD137L (aa 49-254) is fused at the N-terminus to a linker peptide (10 aa) and a FLAG-tag. MW=27kDa.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag
• Protein Length: 49-254 a.a.
• Description: Biologically active CD137L (4-1BBL; TNFSF 9) comprising the whole extracellular tail domain (aa 49-93), which is important for the cross-linking of the protein that is essential for its biological activity.
• Purity: ≥95% (SDS-PAGE).
• Concentration: 0.1mg/ml after reconstitution.
• Formulation: Lyophilized. Contains PBS and 5% trehalose.
• Endotoxin Content: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
• Reconstitution: Reconstitute with 100µl sterile distilled water. Further dilutions should be made with medium containing 5% fetal calf serum.
• Specificity: Binds to human CD137 (4-1BB).
• Storage: Stable for at least 6 months after receipt when stored at -20°C.
• Handling: After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 [ Homo sapiens ]
• Synonyms: TNFSF9; tumor necrosis factor (ligand) superfamily, member 9; CD137L; 4-1BB-L; TNFSF9; tumor necrosis factor (ligand) superfamily, member 9;receptor 4-1BB ligand; homolog of mouse 4-1BB-L; 4-1BBL; 4-1BB ligand; receptor 4-1BB ligand
• Gene ID: 8744
• mRNA Refseq: NM_003811
• Protein Refseq: NP_003802
• MIM: 606182
• UniProt ID: P41273
• Chromosome Location: 19p13.3
• Pathway: Cytokine-cytokine receptor interaction
• Function: cytokine activity; tumor necrosis factor receptor binding