Recombinant Human Ectodysplasin A, FLAG-tagged
Cat.No. : | EDA-2117H |
Product Overview : | Recombinant Human EDA was produced inE. coli.The extracellular domain of human EDA-A1 (ectodysplasin-A1) (aa 245-391) is fused at the N-terminus to a linker peptide (9 aa) and a FLAG-tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | EDA-2117H |
Description : | The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. |
Source : | E. coli. |
Purity : | ≥95% (SDS-PAGE). |
Formulation : | Lyophilized. Contains PBS. |
Concentration : | 0.1mg/ml after reconstitution. |
Endotoxin Content : | <0.1EU/µg purified protein (LAL test; Bio Whittaker). |
Reconstitution : | Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum. |
Specificity : | Binds to human EDAR (ectodysplasin-A1 receptor). |
Stability : | Stable for at least 6 months after receipt when stored at -20°C. |
Gene Name : | EDA ectodysplasin A [ Homo sapiens ] |
Synonyms : | EDA; ectodysplasin A; ED1; HED; EDA1; EDA2; XHED; XLHED; ED1-A1; ED1-A2; STHAGX1; ectodysplasin-A; ectodermal dysplasia protein; X-linked anhidroitic ectodermal dysplasia protein; ectodermal dysplasia 1, anhidrotic; EDA protein; Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form |
Gene ID : | 1896 |
mRNA Refseq : | NM_001005609 |
Protein Refseq : | NP_001005609 |
MIM : | 300451 |
UniProt ID : | Q92838 |
Chromosome Location : | Xq12-q13.1 |
Pathway : | Cytokine-cytokine receptor interaction |
Function : | protein binding; receptor binding; tumor necrosis factor receptor binding |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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