||Recombinant Mouse Fat Mass And Obesity Associated was expressed inE. coli. The mature peptide of mouse FTO (aa 2-502) is fused at the N-terminus to a His-tag.
||TheFTO (fat mass and obesity-associated) gene is well conserved and found in a single copy in vertebrate species. It is suggested that the FTO protein plays a role in fat cell lipolysis, which may be important in explaining why theFTO gene (and FTO gene variants) is implicated in body weight regulation.
||≥95% (SDS-PAGE). Purified by Ni-NTA column and FPLC (Mono Q column).
||Liquid. 0.2μm-filtered solution in 50mM TRIS-Cl, pH 8.2, containing 150mM sodium chloride.
||Working aliquots are stable for up to 3 months when stored at -20°C.