"Fto" Related Products

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Recombinant Mouse Fat Mass And Obesity Associated, His-tagged

Cat. No.: Fto-2127M
Product Overview: Recombinant Mouse Fat Mass And Obesity Associated was expressed inE. coli. The mature peptide of mouse FTO (aa 2-502) is fused at the N-terminus to a His-tag.
Description: TheFTO (fat mass and obesity-associated) gene is well conserved and found in a single copy in vertebrate species. It is suggested that the FTO protein plays a role in fat cell lipolysis, which may be important in explaining why theFTO gene (and FTO gene variants) is implicated in body weight regulation.
Source: E. coli.
Purity: ≥95% (SDS-PAGE). Purified by Ni-NTA column and FPLC (Mono Q column).
Formulation: Liquid. 0.2μm-filtered solution in 50mM TRIS-Cl, pH 8.2, containing 150mM sodium chloride.
Concentration: ~0.5mg/ml.
Stability: Working aliquots are stable for up to 3 months when stored at -20°C.
Gene Name: Fto fat mass and obesity associated [ Mus musculus ]
Synonyms: Fto; fat mass and obesity associated; AW743446; mKIAA1752; protein fto; protein fatso; OTTMUSP00000031320; fat mass and obesity-associated protein
Gene ID: 26383
mRNA Refseq: NM_011936
Protein Refseq: NP_036066
UniProt ID: Q8BGW1
Chromosome Location: 8 C5; 8 41.9 cM
Function: DNA demethylase activity; molecular_function

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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