Recombinant Human FTO, GST-tagged
Cat.No. : | FTO-118H |
Product Overview : | Human FTO full-length ORF ( AAH01284.1, 1 a.a. - 139 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 41.8 kDa |
AA Sequence : | MGHPRAIQPSVFFSPYDVHFLLYPI RCPYLKIGRFHIKLKGLHFLFSFLF FFFETQSHSVTRLECSGTISAHCNL CLPGSSNSPASASQVAGTTGTCHHA QLIFVFLAEMGFHHIGQDGLDLNLV IHPPRSPKALGLQA |
Applications : | ELISA; WB-Re; AP; Array |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | FTO fat mass and obesity associated [ Homo sapiens (human) ] |
Official Symbol : | FTO |
Synonyms : | FTO; ALKBH9; fat mass and obesity associated; alpha-ketoglutarate-dependent dioxygenase FTO; protein fto; AlkB homolog 9; fat mass and obesity-associated protein |
Gene ID : | 79068 |
mRNA Refseq : | NM_001080432 |
Protein Refseq : | NP_001073901 |
MIM : | 610966 |
UniProt ID : | Q9C0B1 |
Chromosome Location : | 16q12.2 |
Function : | DNA-N1-methyladenine dioxygenase activity; ferrous iron binding; oxidative DNA demethylase activity |
Products Types
◆ Recombinant Protein | ||
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FTO-3382M | Recombinant Mouse FTO Protein, His (Fc)-Avi-tagged | +Inquiry |
FTO-1055H | Recombinant Human FTO Protein (T32-P505), His tagged | +Inquiry |
FTO-944H | Recombinant Human FTO Protein, His (Fc)-Avi-tagged | +Inquiry |
FTO-025H | Recombinant Human FTO Protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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