Cat. No.:	HSPB7-2047H
Product Overview:	Recombinant human HSPB7 protein fused to His-tag was expressed inE.coliand purified by using conventional chromatography techniques. 20.7kDa (190aa).
Description:	HSPB7 is a member of HSPB (Heat shock protein beta) family. The HSPB family is one of the more diverse families within the group of HSP families. Some members have chaperone-like activities and/or play a role in cytoskeletal stabilization. Some members also show a dynamic, stress-induced translocation to SC35 splicing speckles. HSPB7 constitutively localized to SC35 splicing speckles, driven by its N-terminus. Unlike HSPB1 and HSPB5, that chaperoned heat unfolded substrates and kept them folding competent, HSPB7 did not support refolding.
Source:	E.coli.
Form:	Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 200mM NaCl, 2mM DTT, 50% glycerol.
Purity:	> 85% by SDS - PAGE.
Concentration:	0.25 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids:	MGSSHHHHHH SSGLVPRGSH MSHRTSSTFR AERSFHSSSS SSSSSTSSSA SRALPAQDPP MEKALSMFSD DFGSFMRPHS EPLAFPARPG GAGNIKTLGD AYEFAVDVRD FSPEDIIVTT SNNHIEVRAE KLAADGTVMN TFAHKCQLPE DVDPTSVTSA LREDGSLTIR ARRHPHTEHVQQTFRTEIKI.
Storage:	Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Name:	HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) [ Homo sapiens ]
Synonyms:	heat shock 27kDa protein family, member 7 (cardiovascular); cvHSP; FLJ32733; DKFZp779D0968; HSPB7; heat shock protein beta-7; cardiovascular heat shock protein; heat shock 27kD protein family, member 7 (cardiovascular); Cardiovascular heat shock protein; cvHsp; HspB7
Gene ID:	27129
mRNA Refseq:	NM_014424
Protein Refseq:	NP_055239
MIM:	610692
UniProt ID:	Q9UBY9
Chromosome Location:	1p36.23-p34.3
Function:	protein C-terminus binding; protein binding

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