Recombinant Human BCL2-Associated Athanogene

• Cat.No.: BAG1-2057H
• Product Overview: Recombinant human BAG1 was expressed inE.coliand purified by using conventional chromatography techniques. 25.9 kDa (230aa).

Specification

• Cat. No.: BAG1-2057H
• Description: BCL2-associated athanogene, also known as BAG1, is a member of the Bcl-2 family of proteins that play varied stimulatory or inhibitory roles in the regulation of programmed cell death. This functions in conjunction with Bcl-2 to inhibit apoptosis. Also, BAG1 has been implicated in age related neurodegenerative diseases as Alzheimer"s. It is localized to the cytosol, nucleus or both.
• Source: E.coli.
• Form: Liquid. In 20mM Tris-HCl buffer (pH7.5) containing 100mM NaCl, 10% glycerol.
• Purity: > 90% by SDS - PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MNRSQEVTRD EESTRSEEVT REEMAAAGLT VTVTHSNEKH DLHVTSQQGS SEPVVQDLAQ VVEEVIGVPQ SFQKLIFKGK SLKEMETPLSALGIQDGCRV MLIGKKNSPQ EEVELKKLKH LEKSVEKIAD QLEELNKELT GIQQGFLPKD LQAEALCKLD RRVKATIEQF MKILEEIDTLILPENFKDSR LKRKGLVKKV QAFLAECDTV EQNICQETER LQSTNFALAE.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: BAG1 BCL2-associated athanogene [ Homo sapiens ]
• Synonyms: BAG1; BCL2-associated athanogene; RAP46; BAG-1; HAP; BCL2-associated athanogene 1; Bcl-2-associated athanogene 1; Glucocorticoid receptor-associated protein RAP46
• Gene ID: 573
• mRNA Refseq: NM_004323
• Protein Refseq: NP_004314
• MIM: 601497
• UniProt ID: Q99933
• Chromosome Location: 9p12
• Function: protein binding; receptor signaling protein activity