Recombinant Human BCL2-Associated Athanogene BAG1-2057H

Recombinant Human BCL2-Associated Athanogene

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Recombinant Human BCL2-Associated Athanogene

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Cat. No. : BAG1-2057H
Product Overview : Recombinant human BAG1 was expressed inE.coliand purified by using conventional chromatography techniques. 25.9 kDa (230aa).
Description : BCL2-associated athanogene, also known as BAG1, is a member of the Bcl-2 family of proteins that play varied stimulatory or inhibitory roles in the regulation of programmed cell death. This functions in conjunction with Bcl-2 to inhibit apoptosis. Also, BAG1 has been implicated in age related neurodegenerative diseases as Alzheimer"s. It is localized to the cytosol, nucleus or both.
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer (pH7.5) containing 100mM NaCl, 10% glycerol.
Purity : > 90% by SDS - PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MNRSQEVTRD EESTRSEEVT REEMAAAGLT VTVTHSNEKH DLHVTSQQGS SEPVVQDLAQ VVEEVIGVPQ SFQKLIFKGK SLKEMETPLSALGIQDGCRV MLIGKKNSPQ EEVELKKLKH LEKSVEKIAD QLEELNKELT GIQQGFLPKD LQAEALCKLD RRVKATIEQF MKILEEIDTLILPENFKDSR LKRKGLVKKV QAFLAECDTV EQNICQETER LQSTNFALAE.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
PDB rendering based on 1hx1. :

Gene Name : BAG1 BCL2-associated athanogene [ Homo sapiens ]
Synonyms : BAG1; BCL2-associated athanogene; RAP46; BAG-1; HAP; BCL2-associated athanogene 1; Bcl-2-associated athanogene 1; Glucocorticoid receptor-associated protein RAP46
Gene ID : 573
mRNA Refseq : NM_004323
Protein Refseq : NP_004314
MIM : 601497
UniProt ID : Q99933
Chromosome Location : 9p12
Function : protein binding; receptor signaling protein activity

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